Navigate to the root directory where you installed the game (usually C:\Program Files (x86)\KONAMI\Pro Evolution Soccer 2013 ). Right-click on the pes2013.exe file and select . Switch to the Compatibility tab.
Sometimes, antivirus software flags "No-CD" patches as "false positives" because they modify an executable file. If the game fails to launch after you've applied a fix, check your antivirus quarantine folder and add an exception for the PES 2013 folder.
If you are a purist who wants to use your original disc on a modern laptop without a drive, the hardware solution is simple and cheap.