To understand the value of this textbook, one must first appreciate the institution behind it. McMaster University in Hamilton, Ontario, is widely recognized as the birthplace of evidence-based medicine. In the late 20th century, the McMaster approach revolutionized medical practice by shifting the paradigm from "expert opinion" and unsystematic clinical experience to a rigorous reliance on the best available evidence. The McMaster Textbook of Internal Medicine is the direct descendant of this philosophy. Unlike traditional textbooks, which often present medical knowledge as absolute dogma, the McMaster text embraces the probabilistic nature of diagnosis and treatment. A PDF version of this work, therefore, is not just a digitized book; it is a portable manifesto of the EBM movement.

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Ischemic heart disease, heart failure, and arrhythmias.